Manzo Antonio - Dipartimento di Medicina interna e terapia medica

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Antonio Manzo

Professore Associato

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Unità di Reumatologia c/o Policlinico San Matteo - Reparti Speciali

Telefono	+ 39 0382 501878
Fax	+ 39 0382 503171
E-mail	antonio.manzo@unipv.it
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Curriculum	CURRICULUM MANZO
Pubblicazioni	1. Bugatti S, Vitolo B, Caporali R, Montecucco C, Manzo A. B Cells in Rheumatoid Arthritis: From Pathogenic Players to Disease Biomarkers. Biomed Res Int. 2014;2014:681678. 2. Bugatti S, Manzo A, Vitolo B, Benaglio F, Binda E, Scarabelli M, Humby F, Caporali R, Pitzalis C, Montecucco C. High expression levels of the B cell chemoattractant CXCL13 in rheumatoid synovium are a marker of severe disease. Rheumatology (Oxford). 2014 Apr 24. [Epub ahead of print] 3. Bugatti S, Manzo A, Benaglio F, Klersy C, Vitolo B, Todoerti M, Sakellariou G, Montecucco C, Caporali R. Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugs. Arthritis Res Ther. 2012; 15;14(1):R34. 4. Manzo A, Caporali R, Vitolo B, Alessi S, Benaglio F, Todoerti M, Bugatti S, Calliada F, Montecucco C. Subclinical remodelling of draining lymph nodestructure in early and established rheumatoid arthritis assessed by power Dopplerultrasonography. Rheumatology (Oxford). 2011;50(8):1395-400. 5. Manzo A, Bombardieri M, Humby F, Pitzalis C. Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling. Immunol Rev. 2010;233(1):267-85. 6. Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil N, Marrelli A, Gould D, Subang C, Al-Kashi A, De Bari C, Winyard P, Chernajovsky Y, Nissim A. Human single-chain variable fragment that specifically targets arthritic cartilage. Arthritis Rheum. 2010;62(4):1007-16. 7. Humby F, Bombardieri M, Manzo A, Kelly S, Blades MC, Kirkham B, Spencer J, Pitzalis C. Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium. PLoS Med. 2009;6(1):e1. 8. Manzo A, Vitolo B, Humby F, Caporali R, Jarrossay D, Dell'accio F, Ciardelli L, Uguccioni M, Montecucco C, Pitzalis C. Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint. Arthritis Rheum. 2008;58(11):3377-87. 9. Manzo A, Bugatti S, Caporali R, Prevo R, Jackson DG, Uguccioni M, Buckley CD, Montecucco C, Pitzalis C. CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesis. Am J Pathol. 2007;171(5):1549-62. 10. Manzo A, Paoletti S, Carulli M, Blades MC, Barone F, Yanni G, Fitzgerald O, Bresnihan B, Caporali R, Montecucco C, Uguccioni M, Pitzalis C. Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis. Eur J Immunol. 2005;35(5):1347-59.
Collaborazioni	1. Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine, London, UK (Prof. Costantino Pitzalis). 2. Institute for Research in Biomedicine, Bellinzona, Svizzera (Dr. Mariagrazia Uguccioni). 3. Bone and Joint Research Unit, William Harvey Research Institute, Barts and the London School of Medicine, London, UK (Dr. Ahuva Nissim). 4. Reumatologia pediatrica, Ospedale Pediatrico Bambino Gesù, Roma (Dr. Fabrizio De Benedetti). 5. Centre for Translational Inflammation Research, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, UK (Prof. Chris Buckley - Dr. Francesca Barone).

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