Dipartimento di Medicina interna e terapia medica

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Pubblicazioni dell'Unità

2019
Palladini G,
Di Pasqua LG, Berardo C, Siciliano V, Richelmi P, Perlini S, Ferrigno A, Vairetti M.
Animal models of steatosis (NAFLD) and steatohepatitis (NASH) exhibit hepatic lobe-specific gelatinases activity and oxidative stress.
Can J. Gastroenterol. Hepatol. 2019 Feb.3; 2019:5413461, doi: 10.1155/2019/5413461. eCollection 2019. PMID: 30854350.   PDF

Palladini G, Di Pasqua LG, Berardo C, Siciliano V, Richelmi P, Mannucci B, Croce AC, Rizzo V, Perlini S, Vairetti M, Ferrigno A. Fatty acid desaturase involvement in non-alcoholic fatty liver disease rat models: oxidative stress versus metalloproteinases.
Nutrients. 2019 Apr. 8;11(4). pii: E799. doi: 10.3390/nu11040799.   PDF

2018
Croce AC, Bottiroli G, Di Pasqua LG, Berardo C, Siciliano V, Rizzo V, Vairetti M, Ferrigno A. Serum and hepatic autofluorescence as a real-time diagnostic tool for early cholestasis assessment.
Int J Mol Sci. 2018 Sep 5;19(9). pii: E2634. doi: 10.3390/ijms19092634.  PDF

Croce AC, Ferrigno A, Bottiroli G, Vairetti M. Autofluorescence-based optical biopsy: an effective diagnostic tool in hepatology.
Liver Int. 2018 Jul;38(7):1160-1174. doi: 10.1111/liv.13753. Epub 2018 Apr 24. Review.  PDF

Ferrigno A
Berardo C, Di Pasqua LG, Siciliano V, Richelmi P, Nicoletti F, Vairetti M. Selective blockade of the metabotropic glutamate receptor mGluR5 protects mouse livers in in vitro and ex vivo models of ischemia reperfusion injury.
Int. Mol. Sci.; 2018 Jan 23:19(2). pii:E314 doi:10.3390/ijms 19020314. PMID: 29360756.  PDF

Ferrigno A
, Di Pasqua LG, Berardo C, Siciliano V, Rizzo V, Adorini L, Richelmi P, Vairetti M. The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.
PLoS One. 2018; 13(1):e0191430. doi:10.1371/journal.pone.0191430 eCollection 2017 PMID: 29346429.  PDF

2017
Ferrigno A
, Di Pasqua LG, Berardo C, Siciliano V, Rizzo V, Mannucci B, Richelmi P, Croce AC, Vairetti M. Liver graft susceptibility during static storage and dynamic machine perfusion: DCD versus fatty livers.
Int. J. Mol. Sci.; 19(1): E109.  PDF

Berardo C, Di Pasqua LG, Siciliano V, Rizzo V, Richelmi P, Vairetti M. Machine perfusione at 20°C prevent ischemic injury and reduces hypoxia-inducible factor-1-alfa expression during rat liver preservation.
Ann. Trasplant. 2017;29(22):581-589.  PDF

Ferrigno A
, Berardo C, Di Pasqua LG, Siciliano V, Richelmi P, Vairetti M. Localization and role of metabotropic glutamate receptors subtype 5 in the gastrointestinal tract.
World J Gastroenterol. 2017; 23(25): 4500-4507.  PDF

Croce AC, Ferrigno A, Di Pasqua L, Berardo C, Bottiroli G, Vairetti M. NAD(P)H and flavin autofluorescence correlation with ATP in rat livers with different metabolic steady-state conditions.
Photochem. Photobiol. 2017; 93(6):1519-1524.    PDF

Ferrigno A, Di Pasqua LG, Berardo C, Siciliano V, Richelmi P, Vairetti M. Oxygen tension-independent protection against hypoxic cell kinng in rat liver by low sodium.
Eur. J. of Histochemistry 2017; 61:2798    PDF

Vairetti M, Ferrigno A, Gringeri E, Cillo U. Representing subnormothermic perfusion in fatty livers: the complete picture?
Am. J. Transplant.  2017(5):1421-1422.   PDF

2016
Croce AC, Ferrigno A, Di Pasqua LG, Berardo C, Mannucci B, Bottiroli G, Vairetti M. Fluorescing fatty acids in rat fatty liver models.
J. Biophotonics, 2016 Dec 16.doi:10.1002.   PDF

Croce AC, Ferrigno A, Di Pasqua LG, Berardo C, Piccolini VM, Bertone V, Bottiroli G, Vairetti M. Autofluorescence discrimination of metabolic fingerprint in nutritional and genetic fatty liver models.
J. Photochem. Photobiol. B. 2016 Nov. 164:13-20.   PDF

Croce AC, Ferrigno A, Bertone V, Piccolini VM, Berardo C, Di Pasqua LG, Rizzo V, Bottiroli G, Vairetti M. Fatty liver oxidative events monitored by autofluorescence optical diagnosis: comparison between subnormothermic machine perfusion and conventional cold storage preservation.
Hepatol. Res. 2016 Jul 23.doi:10.1111.   PDF

Di Pasqua LG, Berardo C, Rizzo V, Richelmi P, Croce AC, Vairetti M, Ferrigno A. MCD diet-induced steatohepaatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters.
Mol. Cell. Biochem. 2016 Aug 419: 147-55.   PDF

Freitas I, Boncompagni E, Tarantola E, Gruppi C, Bertone V, Ferrigno A, Milanesi G, Vaccarone R, Tira ME, Vairetti M. In situ evaluation of oxidative stress in rat fatty liver induced by a methionine-and choline-deficient diet.
Oxid. Med. Cell. Longev. 2016:9307064.doi10.1155.    PDF

Ferrigno A, Di Pasqua LG, Berardo C, Rizzo V, Richelmi P, Vairetti M.Changes in biliary levels of arginine and its methylated derivatives afetr hepatic ischemia/reperfusion.
Basic Clin. Pharmacol. Toxicol. 2016 Jul; 119(1):101-9.doi:10.1111.    PDF

2015
Vairetti M, Jaeschke H, Monbaliu D, Kim JS, Ferrigno A. Innovative pharmacological approaches against hepatic ischemia reperfusion injury.
Biomed. Res. Int.  2015:918583.  PDF

Ferrigno A, Di Pasqua LG, Berardo C, Rizzo V, Richelmi P, Vairetti M. Changes in biliary levels of arginine and its methylated derivatives after hepatic ischaemia referfusion.
Basic Clin Pharmacol Toxicol 2015 Dec12.   PDF

Palladini G, Ferrigno A, Richelmi P, Perlini S, Vairetti M. Role of matrix metalloproteinases in cholestasis and hepatic ischemia reperfusion injury: a review
World J Gatroenterol 2015 Nov 14;21(42):12114-24.   PDF

Ferrigno A, Di Pasqua LG, Berardo C, Richelmi P, Vairetti M. Liver plays a central role in asymmetric dimethylarginine-mediated organ injury.
World J Gastroenterol. 2015 May 7;21(17):5131-7. doi: 10.3748/wjg.v21.i17.5131.    PDF

Ferrigno A, Vairetti M, Ambrosi G, Rizzo V, Richelmi P, Blandini F, Armentero MT. Selective blockade of mGlu5 metabotropic glutamate receptors is protective against hepatic mitochondrial dysfunction in 6-OHDA lesioned Parkinsonian rats.
Clin Exp Pharmacol Physiol. 2015 Apr 23. doi: 10.1111/1440-1681.12410.

Ferrigno A, Di Pasqua LG, Bianchi A, Richelmi P, Vairetti M. Metabolic shift in liver: correlation between perfusion temperature and hypoxia inducible factor-1α.
World J Gastroenterol. 2015 Jan 28;21(4):1108-16. doi: 10.3748/wjg.v21.i4.1108.   PDF

2014
Imberti R, Ferrigno A, Tartaglia A, Rizzo V, Richelmi P, Vairetti M. Changes in extra- and intracellular pH in hepatocytes exposed to gabexate mesilate.
Int J Immunopathol Pharmacol. 2014 Jul-Sep;27(3):365-70.  PDF

Ferrigno A, Rizzo V, Bianchi A, Di Pasqua LG, Berardo C, Richelmi P, Vairetti M. Changes in ADMA/DDAH pathway after hepatic ischemia/reperfusion injury in rats: the role of bile.
Biomed Res Int. 2014;2014:627434. doi: 10.1155/2014/627434. Epub 2014 Aug 27.   PDF

Ferrigno A, Palladini G, Bianchi A, Rizzo V, Di Pasqua LG, Perlini S, Richelmi P, Vairetti M. Lobe-specific heterogeneity in asymmetric dimethylarginine and matrix metalloproteinase levels in a rat model of obstructive cholestasis.
Biomed Res Int.
2014;2014:327537.  PDF

Palladini G, Ferrigno A, Rizzo V, Tarantola E, Bertone V, Freitas I, Perlini S, Richelmi P, Vairetti M. Lung matrix metalloproteinase activation following partial hepatic ischemia/reperfusion injury in rats. ScientificWorld Journal. 2014, 867548. doi: 10.1155/2014/867548.  PDF

2013
Ferrigno A, Richelmi P, Vairetti M. Troubleshooting and improving the mouse and rat isolated perfused liver preparation.
J
Pharmacol Toxicol Methods. 2013;67(2):107-14. doi: 10.1016/j.vascn.2012.10.001. Epub 2012 Oct 16. PMID: 23079697.  PDF

2012
Vairetti M, Ferrigno A, Rizzo V, Ambrosi G, Bianchi A, Richelmi P, Blandini F, Armentero MT. Impaired hepatic function and central dopaminergic denervation in a rodent model of Parkinson's disease: a self-perpetuating crosstalk?
Biochim. Biophys. ACTA. 2012; 1822:176-184.   PDF

Palladini G, Ferrigno A, Rizzo V, Boncompagni E, Richelmi P, Freitas I, Perlini S,Vairetti M. Lobe-specific heterogeneity and matrix metalloproteinase activation after ischemia/reperfusion injury in rat livers. Toxicol. Pathol. 2012;40(5):722-30.  PDF

Ferrigno A, Rizzo V, Boncompagni E, Bianchi A, Richelmi P, Gringeri E, Neri D, Freitas I, Cillo U, Vairetti M. Machine perfusion at 20 degrees C reduces preservation damage to livers from non-heart beating donors.
Cryobiology 2011, 62: 152-158.   PDF

2010
Ferrigno A, Gregotti C, Richelmi P, G Vairetti M. Dexamethasone protects cultured rat hepatocytes against cadmium toxicity: involvement of cellular thiols.
In vitro Cell. Dev. Biol. Anim. 2010; 46(5):445-449.